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Structural and functional insights into nuclear receptor signaling

Nuclear receptors are important transcriptional factors that share high sequence identity and conserved domains, including a DNA-binding domain (DBD) and a ligand-binding domain (LBD). The LBD plays a crucial role in ligand-mediated nuclear receptor activity. Hundreds of different crystal structures...

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Detalhes bibliográficos
Main Authors: Jin, Lihua, Li, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991384/
https://ncbi.nlm.nih.gov/pubmed/20723571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2010.08.007
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