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Structural and functional insights into nuclear receptor signaling
Nuclear receptors are important transcriptional factors that share high sequence identity and conserved domains, including a DNA-binding domain (DBD) and a ligand-binding domain (LBD). The LBD plays a crucial role in ligand-mediated nuclear receptor activity. Hundreds of different crystal structures...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991384/ https://ncbi.nlm.nih.gov/pubmed/20723571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2010.08.007 |
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