Prevention of Paclitaxel-induced allodynia by Minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats

BACKGROUND: Although paclitaxel is a frontline antineoplastic agent for treatment of solid tumors, the paclitaxel-evoked pain syndrome is a serious problem for patients. There is currently no valid drug to prevent or treat the paclitaxel-induced allodynia, partly due to lack of understanding regardi...

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Hlavní autoři: Liu, Cui-Cui, Lu, Ning, Cui, Yu, Yang, Tao, Zhao, Zhi-Qi, Xin, Wen-Jun, Liu, Xian-Guo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991291/
https://ncbi.nlm.nih.gov/pubmed/21050491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-76
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