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Versatile methodology for the synthesis and α-functionalization of (2R,3aS,7aS)-octahydroindole-2-carboxylic acid

An improved strategy for the effective synthesis of enantiomerically pure (2R,3aS,7aS)-octahydroindole-2-carboxylic acid (Oic), based on the formation of a trichloromethyloxazolidinone derivative, has been developed. Additionally, the completely diastereoselective α-alkylation of such oxazolidinone...

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Detalles Bibliográficos
Main Authors: Sayago, Francisco J., Calaza, M. Isabel, Jiménez, Ana I., Cativiela, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991158/
https://ncbi.nlm.nih.gov/pubmed/21113401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.10.095
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