Cytochrome P450 2D6 Activity Predicts Discontinuation of Tamoxifen Therapy in Breast Cancer Patients

The selective estrogen receptor modulator tamoxifen is routinely used for treatment and prevention of estrogen receptor positive breast cancer. Studies of tamoxifen adherence suggest that over half of patients discontinue treatment before the recommended 5 years. We hypothesized that polymorphisms i...

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Bibliographische Detailangaben
Hauptverfasser: Rae, James M., Sikora, Matthew J., Henry, N. Lynn, Li, Lang, Kim, Seongho, Oesterreich, Steffi, Skaar, Todd, Nguyen, Anne T., Desta, Zeruesenay, Storniolo, Anna Maria, Flockhart, David A., Hayes, Daniel F., Stearns, Vered
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991048/
https://ncbi.nlm.nih.gov/pubmed/19421167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2009.14
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