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Simvastatin Inhibits Goblet Cell Hyperplasia and Lung Arginase in a Mouse Model of Allergic Asthma: A Novel Treatment for Airway Remodeling?

Airway remodeling in asthma contributes to airway hyperreactivity, loss of lung function, and persistent symptoms. Current therapies do not adequately treat the structural airway changes associated with asthma. The statins are cholesterol-lowering drugs that inhibit the enzyme 3-hydroxy-3-methyl-glu...

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書誌詳細
主要な著者: Zeki, Amir A., Bratt, Jennifer M., Rabowsky, Michelle, Last, Jerold A., Kenyon, Nicholas J.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990975/
https://ncbi.nlm.nih.gov/pubmed/21078495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2010.09.003
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