Endotoxin-induced lung injury in α-galactosylceramide-sensitized mice is caused by failure of interleukin-4 production in lung natural killer T cells

Administration of bacterial lipopolysaccharide (LPS) known as endotoxin into α-galactosylceramide (α-GalCer)-sensitized mice causes severe lung lesions but few hepatic lesions in lethal shock, and interferon (IFN)-γ is suggested to play a pivotal role in preparation of the lung lesions. In order to...

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Autors principals: Dagvadorj, J, Tumurkhuu, G, Naiki, Y, Noman, A S M, Iftakhar-E-Khuda, I, Badamtseren, B, Komatsu, T, Koide, N, Yoshida, T, Yokochi, T
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2010
Matèries:
Animal Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990943/
https://ncbi.nlm.nih.gov/pubmed/20659123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04225.x
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