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Tumor necrosis factor-α augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation

The regulatory role of tumour necrosis factor-α (TNF-α) on the expression of suppressor of cytokine signalling 3 (SOCS-3) in response to lipopolysaccharide (LPS) was examined using peritoneal macrophages from TNF-α-deficient mice. The LPS-induced SOCS-3 expression was markedly augmented in macrophag...

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Autori principali: Dagvadorj, Jargalsaikhan, Naiki, Yoshikazu, Tumurkhuu, Gantsetseg, Shadat Mohammod Noman, Abu, Iftakhar-E-Khuda, Imtiaz, Komatsu, Takayuki, Koide, Naoki, Yoshida, Tomoaki, Yokochi, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807490/
https://ncbi.nlm.nih.gov/pubmed/20050332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03154.x
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