Novel mechanism of U18666A-induced tumour necrosis factor-α production in RAW 264·7 macrophage cells

U18666A is a cholesterol transport-inhibiting agent that is used widely to mimic Niemann–Pick type C disease. The effect of U18666A on tumour necrosis factor (TNF)-α production in mouse macrophage cell line, RAW 264·7 cells and peritoneal macrophages was examined. U18666A induced TNF-α mRNA expressi...

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Detalhes bibliográficos
Main Authors: Iftakhar-E-Khuda, I, Koide, N, Hassan, F, Noman, A S M, Dagvadorj, J, Tumurkhuu, G, Naiki, Y, Komatsu, T, Yoshida, T, Yokochi, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Basic Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669532/
https://ncbi.nlm.nih.gov/pubmed/19220841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03779.x
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