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Tumor Necrosis Factor-α Represses the Expression of NHE2 Through NF-κB Activation in Intestinal Epithelial Cell Model, C2BBe1
BACKGROUND: High levels of proinflammatory cytokines are linked to pathogenesis of diarrhea in inflammatory bowel diseases (IBD). Na(+) absorption is compromised in IBD. The studies were designed to determine the effect of tumor necrosis factor-α (TNF-α) on the expression and activity of NHE2, a Na(...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990806/ https://ncbi.nlm.nih.gov/pubmed/20722069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21419 |
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