Tumor Necrosis Factor-α Represses the Expression of NHE2 Through NF-κB Activation in Intestinal Epithelial Cell Model, C2BBe1

BACKGROUND: High levels of proinflammatory cytokines are linked to pathogenesis of diarrhea in inflammatory bowel diseases (IBD). Na(+) absorption is compromised in IBD. The studies were designed to determine the effect of tumor necrosis factor-α (TNF-α) on the expression and activity of NHE2, a Na(...

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Bibliographische Detailangaben
Hauptverfasser: AMIN, MD RUHUL, ORENUGA, TEMITOPE, TYAGI, SANGEETA, DUDEJA, PRADEEP K., RAMASWAMY, KRISHNAMURTHY, MALAKOOTI, JALEH
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990806/
https://ncbi.nlm.nih.gov/pubmed/20722069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21419
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