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Sp1 and Sp3 control constitutive expression of the human NHE2 promoter by interactions with the proximal promoter and the transcription initiation site

We have previously cloned the human Na(+)/H(+) exchanger NHE2 gene and its promoter region. In the present study, the regulatory elements responsible for the constitutive expression of NHE2 were studied. Transient transfection assays revealed that the −40/+150 promoter region contains the core promo...

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Bibliographic Details
Main Authors: Pearse, Ian, Zhu, Ying X., Murray, Eleanor J., Dudeja, Pradeep K., Ramaswamy, Krishnamurthy, Malakooti, Jaleh
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267401/
https://ncbi.nlm.nih.gov/pubmed/17561809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070364
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