PKC-dependent stimulation of the human MCT1 promoter involves transcription factor AP2

Monocarboxylate transporter (MCT1) plays an important role in the absorption of short-chain fatty acids (SCFA) such as butyrate in the human colon. Previous studies from our laboratory have demonstrated that phorbol ester, PMA (1 μM, 24 h), upregulates butyrate transport and MCT1 protein expression...

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Autors principals: Saksena, Seema, Dwivedi, Alka, Gill, Ravinder K., Singla, Amika, Alrefai, Waddah A., Malakooti, Jaleh, Ramaswamy, Krishnamurthy, Dudeja, Pradeep K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Mucosal Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643915/
https://ncbi.nlm.nih.gov/pubmed/19033536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90503.2008
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