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PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1
The apical Na(+)/H(+) exchanger (NHE) isoform NHE2 is involved in transepithelial Na(+) absorption in the intestine. Our earlier studies have shown that mitogenic agent phorbol 12-myristate 13-acetate (PMA) induces the expression of NHE2 through activation of transcription factor early growth respon...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287399/ https://ncbi.nlm.nih.gov/pubmed/22052014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00363.2011 |
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