Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2.

In Swiss 3T3 fibroblasts bradykinin stimulated inositol phosphate (InsP) formation and prostaglandin E2 (PGE2) synthesis. The EC50 values for stimulation of PGE2 synthesis and InsP formation by bradykinin were similar, 200 pM and 275 pM, respectively. Guanosine-5'-[gamma-thio]triphosphate stimulated...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Burch, R M, Axelrod, J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1987
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2888113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.18.6374
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