The Thr92Ala 5′ Type 2 Deiodinase Gene Polymorphism Is Associated with a Delayed Triiodothyronine Secretion in Response to the Thyrotropin-Releasing Hormone–Stimulation Test: A Pharmacogenomic Study

BACKGROUND: The common Thr92Ala D2 polymorphism has been associated with changes in pituitary–thyroid axis homeostasis, but published results are conflicting. To investigate the effects of the Thr92Ala polymorphism on intrathyroidal thyroxine (T4) to triiodothyronine (T3) conversion, we designed pro...

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Detaylı Bibliyografya
Asıl Yazarlar: Butler, Peter W., Smith, Sheila M., Linderman, Joyce D., Brychta, Robert J., Alberobello, Anna Teresa, Dubaz, Ornella M., Luzon, Javier A., Skarulis, Monica C., Cochran, Craig S., Wesley, Robert A., Pucino, Frank, Celi, Francesco Saverio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Mary Ann Liebert, Inc. 2010
Konular:
Original Studies, Reviews, and Scholarly Dialog
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990280/
https://ncbi.nlm.nih.gov/pubmed/21054208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.0244
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