Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic β-cell line

Chronic exposure of pancreatic β-cells to saturated non-esterified fatty acids can lead to inhibition of insulin secretion and apoptosis. Several previous studies have demonstrated that saturated fatty acids such as PA (palmitic acid) are detrimental to β-cell function compared with unsaturated fatt...

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Autori principali: Keane, Deirdre C., Takahashi, Hilton K., Dhayal, Shalinee, Morgan, Noel G., Curi, Rui, Newsholme, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990202/
https://ncbi.nlm.nih.gov/pubmed/20840078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20100282
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