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Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells

Pro-inflammatory cytokines are important mediators of β-cell demise in type 1 diabetes, and similar mechanisms are increasingly implicated in type 2 diabetes, where a state of chronic inflammation may persist. It is likely that the actions of anti-inflammatory cytokines are also altered in diabetes....

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Detalhes bibliográficos
Main Authors: Russell, Mark A., Cooper, Angela C., Dhayal, Shalinee, Morgan, Noel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204019/
https://ncbi.nlm.nih.gov/pubmed/23510983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.24249
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