Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays

One way to profile complex mixtures for receptor affinity is to couple liquid chromatography (LC) on-line to biochemical detection (BCD). A drawback of this hyphenated screening approach is the relatively high consumption of sample, receptor protein and (fluorescently labeled) tracer ligand. Here, w...

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Main Authors: Heus, Ferry, Giera, Martin, de Kloe, Gerdien E., van Iperen, Dick, Buijs, Joost, Nahar, Tariq T., Smit, August B., Lingeman, Henk, de Esch, Iwan J. P., Niessen, Wilfried M. A., Irth, Hubertus, Kool, Jeroen
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2010
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Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990015/
https://ncbi.nlm.nih.gov/pubmed/20872136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-4210-x
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