A new ultrafast and high-throughput mass spectrometric approach for the therapeutic drug monitoring of the multi-targeted anti-folate pemetrexed in plasma from lung cancer patients

An analytical assay has been developed and validated for ultrafast and high-throughput mass spectrometric determination of pemetrexed concentrations in plasma using matrix assisted laser desorption/ionization–triple quadrupole–tandem mass spectrometry. Patient plasma samples spiked with the internal...

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Bibliografiska uppgifter
Huvudupphovsmän: Meesters, Roland J. W., Cornelissen, Robin, van Klaveren, Rob J., de Jonge, Robert, den Boer, Ethan, Lindemans, Jan, Luider, Theo M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer-Verlag 2010
Ämnen:
Technical Note
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990004/
https://ncbi.nlm.nih.gov/pubmed/20865407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-4192-8
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