The Proton-Coupled Folate Transporter: Impact on Pemetrexed Transport and on Antifolates Activities Compared to the Reduced Folate Carrier

The reduced folate carrier (RFC) and the proton-coupled folate transporter (PCFT) are ubiquitously expressed in normal and malignant mammalian tissues and in human solid tumor cell lines. This paper addresses the extent to which PCFT contributes to transport of pemetrexed and to the activities of th...

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Hlavní autoři: Zhao, Rongbao, Qiu, Andong, Tsai, Eugenia, Jansen, Michaela, Akabas, Myles H., Goldman, I. David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716086/
https://ncbi.nlm.nih.gov/pubmed/18524888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.045443
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