Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome

Reduced bone mineral density (osteopenia) is a poorly characterized manifestation of pediatric and adult patients afflicted with Marfan syndrome (MFS), a multisystem disorder caused by structural or quantitative defects in fibrillin-1 that perturb tissue integrity and TGFβ bioavailability. Here we r...

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Bibliografiske detaljer
Main Authors: Nistala, Harikiran, Lee-Arteaga, Sui, Carta, Luca, Cook, Jason R., Smaldone, Silvia, Siciliano, Gabriella, Rifkin, Aaron N., Dietz, Harry C., Rifkin, Daniel B., Ramirez, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989889/
https://ncbi.nlm.nih.gov/pubmed/20871099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq409
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