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The Influence of Enrollment Criteria on Recruitment and Outcome Distribution in Traumatic Brain Injury Studies: Results from the Impact Study

Substantial heterogeneity exists among patients who suffer from traumatic brain injury (TBI). Strict enrollment criteria may diminish heterogeneity in randomized controlled trials (RCTs), but will also decrease recruitment and may affect the outcome distribution. The aim of this study was to investi...

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Main Authors: Roozenbeek, Bob, Maas, Andrew I.R., Marmarou, Anthony, Butcher, Isabella, Lingsma, Hester F., Lu, Juan, McHugh, Gillian S., Murray, Gordon D., Steyerberg, Ewout W.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989840/
https://ncbi.nlm.nih.gov/pubmed/19594383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0569
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