IMPACT recommendations for improving the design and analysis of clinical trials in moderate to severe traumatic brain injury

Clinical trials in traumatic brain injury (TBI) pose complex methodological challenges, largely related to the heterogeneity of the population. The International Mission on Prognosis and Clinical Trial Design in TBI study group has explored approaches for dealing with this heterogeneity with the aim...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Maas, Andrew I. R., Steyerberg, Ewout W., Marmarou, Anthony, McHugh, Gillian S., Lingsma, Hester F., Butcher, Isabella, Lu, Juan, Weir, James, Roozenbeek, Bob, Murray, Gordon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084119/
https://ncbi.nlm.nih.gov/pubmed/20129504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.10.020
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