IMPACT recommendations for improving the design and analysis of clinical trials in moderate to severe traumatic brain injury

Clinical trials in traumatic brain injury (TBI) pose complex methodological challenges, largely related to the heterogeneity of the population. The International Mission on Prognosis and Clinical Trial Design in TBI study group has explored approaches for dealing with this heterogeneity with the aim...

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Bibliographische Detailangaben
Veröffentlicht in:Neurotherapeutics
Hauptverfasser: Maas, Andrew I. R., Steyerberg, Ewout W., Marmarou, Anthony, McHugh, Gillian S., Lingsma, Hester F., Butcher, Isabella, Lu, Juan, Weir, James, Roozenbeek, Bob, Murray, Gordon D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084119/
https://ncbi.nlm.nih.gov/pubmed/20129504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nurt.2009.10.020
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