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Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase2: implications for the mechanism of enzyme inhibition
Molinate is a thiocarbamate herbicide used as a pre-emergent in rice patty fields. It has two predominant sulfoxidation metabolites, molinate sulfoxide and molinate sulfone. Previous work demonstrated an in vivo decrease in liver aldehyde dehydrogenase (ALDH) activity in rats treated with molinate a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989800/ https://ncbi.nlm.nih.gov/pubmed/20954713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100317q |
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