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Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling

Interleukin 17 (IL-17) plays critical roles in the pathogenesis of various autoimmune diseases, including experimental autoimmune encephalomyelitis (EAE). How the signals triggered by this powerful inflammatory cytokine are controlled to avoid abnormal inflammatory responses is not well understood....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Shu, Pan, Wen, Shi, Peiqing, Gao, Hanchao, Zhao, Fang, Song, Xinyang, Liu, Yan, Zhao, Lihua, Li, Xiaoxia, Shi, Yufang, Qian, Youcun
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989772/
https://ncbi.nlm.nih.gov/pubmed/21078888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100703
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