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Identification of a polyI:C-inducible membrane protein that participates in dendritic cell–mediated natural killer cell activation
In myeloid dendritic cells (mDCs), TLR3 is expressed in the endosomal membrane and interacts with the adaptor toll/interleukin 1 receptor homology domain–containing adaptor molecule 1 (TICAM-1; TRIF). TICAM-1 signals culminate in interferon (IFN) regulatory factor (IRF) 3 activation. Co-culture of m...
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| Main Authors: | , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The Rockefeller University Press
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989763/ https://ncbi.nlm.nih.gov/pubmed/21059856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091573 |
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