Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent

We showed earlier that experimental autoimmune encephalomyelitis (EAE) in human C-reactive protein (CRP) transgenic mice (CRPtg) has delayed onset and reduced severity compared to wild-type mice. Since human CRP is known to engage Fc receptors and Fc receptors are known to play a role in EAE in the...

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Autores principales: Hu, Xian-Zhen, Wright, Tyler T., Jones, Nicholas R., Ramos, Theresa N., Skibinski, Gregory A., McCrory, Mark A., Barnum, Scott R., Szalai, Alexander J.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989644/
https://ncbi.nlm.nih.gov/pubmed/21151582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/484936
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