Exaggerated Neointima Formation in Human C-Reactive Protein Transgenic Mice Is IgG Fc Receptor Type I (FcγRI)-Dependent

Neointima formation after vascular injury is exaggerated in ovariectomized (OVX) human C-reactive protein transgenic mice (CRPtg) compared to nontransgenic mice (NTG). We tested the hypothesis that this CRP-mediated exacerbation requires IgG Fc receptors (FcγRs). OVX NTG, CRPtg, and CRPtg lacking Fc...

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Detalhes bibliográficos
Main Authors: Xing, Dongqi, Hage, Fadi G., Chen, Yiu-Fai, McCrory, Mark A., Feng, Wenguang, Skibinski, Gregory A., Majid-Hassan, Erum, Oparil, Suzanne, Szalai, Alexander J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189617/
https://ncbi.nlm.nih.gov/pubmed/18063701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070154
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