C-Reactive Protein Mediated Vascular Injury Requires Complement

OBJECTIVES: We previously demonstrated that vascular injury-induced neointima formation is exaggerated in human C-reactive protein transgenic (CRPtg) compared to non-transgenic (NTG) mice. We now test the hypothesis that complement is required for this effect. METHODS AND RESULTS: CRPtg and NTG with...

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Autores principales: Hage, Fadi G., Oparil, Suzanne, Xing, Dongqi, Chen, Yiu-Fai, McCrory, Mark A., Szalai, Alexander J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897052/
https://ncbi.nlm.nih.gov/pubmed/20339115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.205377
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