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Band 3 Catalyzes Sickle Hemoglobin Polymerization

We have measured homogeneous and heterogeneous nucleation rates of sickle hemoglobin (HbS) in the presence of a strongly binding deletion mutant of the cytoplasmic domain of band 3 (cdb3), a membrane protein known to form dimers and to bind 2 HbS molecules to such a dimer, and we find that it accele...

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Bibliographic Details
Main Authors: Rotter, Maria A., Chu, Haiyan, Low, Philip S., Ferrone, Frank A.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989409/
https://ncbi.nlm.nih.gov/pubmed/19880238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2009.10.004
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