Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis.

The predicted amino acid sequences of isopenicillin N synthetase from both Cephalosporium acremonium and Penicillium chrysogenum have two cysteine residues in analogous positions (Cys-106 and Cys-255 in the C. acremonium numbering). To examine the role of these cysteine residues in the activity of t...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Samson, S M, Chapman, J L, Belagaje, R, Queener, S W, Ingolia, T D
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC298931/
https://ncbi.nlm.nih.gov/pubmed/3112774
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