FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma

AIMS: To develop a fluorescence in-situ hybridisation (FISH) assay for detecting p16/CDKN2A deletion on paraffin tissue sections for use as an ancillary test to distinguish reactive from malignant mesothelial proliferations. METHOD: Dual-colour FISH for p16/CDKN2A and chromosome 9 (CEP-9) was perfor...

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Detalhes bibliográficos
Main Authors: Chung, Catherine T-S, Santos, Gilda Da Cunha, Hwang, David M, Ludkovski, Olga, Pintilie, Melania, Squire, Jeremy A, Tsao, Ming-Sound
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989172/
https://ncbi.nlm.nih.gov/pubmed/20591913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2010.076794
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