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Deletion status of p16 in effusion smear preparation correlates with that of underlying malignant pleural mesothelioma tissue

Differentiating malignant pleural mesothelioma (MPM) cells morphologically from reactive mesothelial hyperplasia cells is problematic. Homozygous deletion (HD) of p16 (CDKN2A), detected by FISH, is a good marker of malignancy and is useful to differentiate between these cells. However, the correlati...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Hida, Tomoyuki, Matsumoto, Shinji, Hamasaki, Makoto, Kawahara, Kunimitsu, Tsujimura, Tohru, Hiroshima, Kenzo, Kamei, Toshiaki, Taguchi, Kenichi, Iwasaki, Akinori, Oda, Yoshinao, Honda, Hiroshi, Nabeshima, Kazuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714681/
https://ncbi.nlm.nih.gov/pubmed/26291840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12769
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