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CDKN2A copy number and p16 expression in malignant pleural mesothelioma in relation to asbestos exposure

BACKGROUND: Deletion of the CDKN2A locus is centrally involved in the development of several malignancies. In malignant pleural mesothelioma (MPM), it is one of the most frequently reported genomic alteration. MPM is strongly associated with a patients’ asbestos exposure. However, the status of CDKN...

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Vydáno v:BMC Cancer
Hlavní autoři: Kettunen, Eeva, Savukoski, Sauli, Salmenkivi, Kaisa, Böhling, Tom, Vanhala, Esa, Kuosma, Eeva, Anttila, Sisko, Wolff, Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537412/
https://ncbi.nlm.nih.gov/pubmed/31138176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5652-y
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