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Conformational flexibility of RNA polymerase III during transcriptional elongation

RNA polymerase (Pol) III is responsible for the transcription of genes encoding small RNAs, including tRNA, 5S rRNA and U6 RNA. Here, we report the electron cryomicroscopy structures of yeast Pol III at 9.9 Å resolution and its elongation complex at 16.5 Å resolution. Particle sub-classification rev...

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Hlavní autoři: Fernández-Tornero, Carlos, Böttcher, Bettina, Rashid, Umar Jan, Steuerwald, Ulrich, Flörchinger, Beate, Devos, Damien P, Lindner, Doris, Müller, Christoph W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989110/
https://ncbi.nlm.nih.gov/pubmed/20967027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.266
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