Conformational flexibility of RNA polymerase III during transcriptional elongation

RNA polymerase (Pol) III is responsible for the transcription of genes encoding small RNAs, including tRNA, 5S rRNA and U6 RNA. Here, we report the electron cryomicroscopy structures of yeast Pol III at 9.9 Å resolution and its elongation complex at 16.5 Å resolution. Particle sub-classification rev...

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Main Authors: Fernández-Tornero, Carlos, Böttcher, Bettina, Rashid, Umar Jan, Steuerwald, Ulrich, Flörchinger, Beate, Devos, Damien P, Lindner, Doris, Müller, Christoph W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989110/
https://ncbi.nlm.nih.gov/pubmed/20967027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.266
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