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Tyrosine dephosphorylation is required for Bak activation in apoptosis
Activation of the cell-death mediator Bak commits a cell to mitochondrial apoptosis. The initial steps that govern Bak activation are poorly understood. To further clarify these pivotal events, we have investigated whether post-translational modifications of Bak impinge on its activation potential....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989102/ https://ncbi.nlm.nih.gov/pubmed/20959805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.244 |
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