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A phase I evaluation of the combination of vinflunine and erlotinib in patients with refractory solid tumors
PURPOSE: Epidermal growth factor receptor (EGFR) inhibition may overcome chemotherapy resistance by inhibiting important anti-apoptotic signals that are constitutively activated by an overstimulated EGFR pathway. METHODS: This phase I dose escalation trial assessed the safety and efficacy of vinflun...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988886/ https://ncbi.nlm.nih.gov/pubmed/20387090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9427-1 |
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