A phase I evaluation of the combination of vinflunine and erlotinib in patients with refractory solid tumors

PURPOSE: Epidermal growth factor receptor (EGFR) inhibition may overcome chemotherapy resistance by inhibiting important anti-apoptotic signals that are constitutively activated by an overstimulated EGFR pathway. METHODS: This phase I dose escalation trial assessed the safety and efficacy of vinflun...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sanoff, Hanna K., Davies, Janine M., Walko, Christine, Irvin, William, Buie, Larry, Keller, Kimberly, Ivanova, Anastasia, Chiu, Wing-Keung, O'Neil, Bert H., Stinchcombe, Thomas E., Dees, E. Claire
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988886/
https://ncbi.nlm.nih.gov/pubmed/20387090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9427-1
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia