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Human ASPM participates in spindle organisation, spindle orientation and cytokinesis
BACKGROUND: Mutations in the Abnormal Spindle Microcephaly related gene (ASPM) are the commonest cause of autosomal recessive primary microcephaly (MCPH) a disorder characterised by a small brain and associated mental retardation. ASPM encodes a mitotic spindle pole associated protein. It is suggest...
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| Asıl Yazarlar: | , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988714/ https://ncbi.nlm.nih.gov/pubmed/21044324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-85 |
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