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MOLECULAR IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF A MITOCHONDRIAL SUR2 SPLICE VARIANT GENERATED BY INTRA-EXONIC SPLICING

RATIONALE: Cardioprotective pathways may involve a mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) but its composition is not fully understood. OBJECTIVE: We hypothesized that mitoK(ATP) contains a SUR2 regulatory subunit and aimed to identify the molecular structure. METHODS & RESULT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ye, Bin, Kroboth, Stacie, Pu, Jie-Lin, Sims, Jason, Aggarwal, Nitin, McNally, Elizabeth, Makielski, Jonathan, Shi, Nian-Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988690/
https://ncbi.nlm.nih.gov/pubmed/19797704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.195040
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