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The mitochondrial bioenergetic phenotype for protection from cardiac ischemia in SUR2 mutant mice

The sulfonylurea receptor-2 (SUR2) is a subunit of ATP-sensitive potassium channels (K(ATP)) in heart. Mice with the SUR2 gene disrupted (SUR2m) are constitutively protected from ischemia-reperfusion (I/R) cardiac injury. This was surprising because K(ATP), either sarcolemmal or mitochondrial or bot...

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Bibliografische gegevens
Hoofdauteurs: Aggarwal, Nitin T., Pravdic, Danijel, McNally, Elizabeth M., Bosnjak, Zeljko J., Shi, Nian-Qing, Makielski, Jonathan C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006279/
https://ncbi.nlm.nih.gov/pubmed/20935152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00363.2010
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