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Channel-Opening Kinetic Mechanism for Human Wild-Type GluK2 and the M867I Mutant Kainate Receptor

GluK2 is a kainate receptor subunit that is alternatively spliced at the C-terminus. Previous studies implicated GluK2 in autism. In particular, the methionine-to-isoleucine replacement at amino acid residue 867 (M867I) that can only occur in the longest isoform of the human GluK2 (hGluK2), as the d...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Han, Yan, Wang, Congzhou, Park, Jae Seon, Niu, Li
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988652/
https://ncbi.nlm.nih.gov/pubmed/20863077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100819v
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