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Hypoxia Increases the Dependence of Glioma Cells on Glutathione

Glutathione (GSH) is an essential antioxidant responsible for the maintenance of intracellular redox homeostasis. As tumors outgrow their blood supply and become hypoxic, their redox homeostasis is challenged by the production of nitric oxide and reactive oxygen species (ROS). In gliomas, the sustai...

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Autores principales: Ogunrinu, Toyin Adeyemi, Sontheimer, Harald
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988376/
https://ncbi.nlm.nih.gov/pubmed/20858898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161190
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