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Hypoxia Increases the Dependence of Glioma Cells on Glutathione
Glutathione (GSH) is an essential antioxidant responsible for the maintenance of intracellular redox homeostasis. As tumors outgrow their blood supply and become hypoxic, their redox homeostasis is challenged by the production of nitric oxide and reactive oxygen species (ROS). In gliomas, the sustai...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988376/ https://ncbi.nlm.nih.gov/pubmed/20858898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161190 |
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