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Hypoxia Increases the Dependence of Glioma Cells on Glutathione
Glutathione (GSH) is an essential antioxidant responsible for the maintenance of intracellular redox homeostasis. As tumors outgrow their blood supply and become hypoxic, their redox homeostasis is challenged by the production of nitric oxide and reactive oxygen species (ROS). In gliomas, the sustai...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988376/ https://ncbi.nlm.nih.gov/pubmed/20858898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161190 |
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