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Autocrine Glutamate Signaling Promotes Glioma Cell Invasion

Malignant gliomas have been shown to release glutamate, which kills surrounding brain cells, creating room for tumor expansion. This glutamate release occurs primarily via system [Formula: see text] , a Na(+)-independent cystine-glutamate exchanger. We show here, in addition, that the released gluta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lyons, Susan A., Joon Chung, W., Weaver, Amy K., Ogunrinu, Toyin, Sontheimer, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045073/
https://ncbi.nlm.nih.gov/pubmed/17909056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-2034
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