Altered DNA Methylation in Leukocytes with Trisomy 21

The primary abnormality in Down syndrome (DS), trisomy 21, is well known; but how this chromosomal gain produces the complex DS phenotype, including immune system defects, is not well understood. We profiled DNA methylation in total peripheral blood leukocytes (PBL) and T-lymphocytes from adults wit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kerkel, Kristi, Schupf, Nicole, Hatta, Kota, Pang, Deborah, Salas, Martha, Kratz, Alexander, Minden, Mark, Murty, Vundavalli, Zigman, Warren B., Mayeux, Richard P., Jenkins, Edmund C., Torkamani, Ali, Schork, Nicholas J., Silverman, Wayne, Croy, B. Anne, Tycko, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987931/
https://ncbi.nlm.nih.gov/pubmed/21124956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001212
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados