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Elevated plasma amyloid β-peptide Aβ42, incident dementia and mortality in Down syndrome

BACKGROUND: Deposition of the amyloid beta peptide, Aβ42, is thought to be an important initial step in the pathogenesis of Alzheimer’s disease. Individuals with Down syndrome have both increased levels of Aβ peptides and increased risk for Alzheimer’s disease. OBJECTIVE: To examine the relation of...

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Detalhes bibliográficos
Main Authors: Schupf, Nicole, Patel, Bindu, Pang, Deborah, Zigman, Warren B., Silverman, Wayne, Mehta, Pankaj D., Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587094/
https://ncbi.nlm.nih.gov/pubmed/17620492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.64.7.1007
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