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Elevated plasma amyloid β-peptide Aβ42, incident dementia and mortality in Down syndrome

BACKGROUND: Deposition of the amyloid beta peptide, Aβ42, is thought to be an important initial step in the pathogenesis of Alzheimer’s disease. Individuals with Down syndrome have both increased levels of Aβ peptides and increased risk for Alzheimer’s disease. OBJECTIVE: To examine the relation of...

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Библиографические подробности
Главные авторы: Schupf, Nicole, Patel, Bindu, Pang, Deborah, Zigman, Warren B., Silverman, Wayne, Mehta, Pankaj D., Mayeux, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587094/
https://ncbi.nlm.nih.gov/pubmed/17620492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.64.7.1007
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