Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21

BACKGROUND: Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood. METHODS: We used oligonucleotide microarrays to survey mRNA expression in early- and late-passage control and +21 fibrobl...

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Main Authors: Li, Chi-Ming, Guo, Meirong, Salas, Martha, Schupf, Nicole, Silverman, Wayne, Zigman, Warren B, Husain, Sameera, Warburton, Dorothy, Thaker, Harshwardhan, Tycko, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435874/
https://ncbi.nlm.nih.gov/pubmed/16539728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-7-24
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