Trisomy 21 enhances human fetal erythro-megakaryocytic development

Children with Down syndrome exhibit 2 related hematopoietic diseases: transient myeloproliferative disorder (TMD) and acute megakaryoblastic leukemia (AMKL). Both exhibit clonal expansion of blasts with biphenotypic erythroid and megakaryocytic features and contain somatic GATA1 mutations. While alt...

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Detaylı Bibliyografya
Asıl Yazarlar: Chou, Stella T., Opalinska, Joanna B., Yao, Yu, Fernandes, Myriam A., Kalota, Anna, Brooks, John S. J., Choi, John K., Gewirtz, Alan M., Danet-Desnoyers, Gwenn-ael, Nemiroff, Richard L., Weiss, Mitchell J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Hematopoiesis and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597125/
https://ncbi.nlm.nih.gov/pubmed/18812473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157859
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